F-box protein FBXO31 is down-regulated in gastric cancer and negatively regulated by miR-17 and miR-20a
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چکیده
منابع مشابه
F-box protein FBXO31 is down-regulated in gastric cancer and negatively regulated by miR-17 and miR-20a
FBXO31, a subunit of the SCF ubiquitin ligase, played a crucial role in neuronal development, DNA damage response and tumorigenesis. Here, we investigated the expression and prognosis value of FBXO31 in human primary gastric cancer (GC) samples. Meanwhile, the biological role and the regulation mechanism of FBXO31 were evaluated. We found that FBXO31 mRNA and protein was decreased dramatically ...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2014
ISSN: 1949-2553
DOI: 10.18632/oncotarget.2183